Questions about Clomid
What is Clomid?
Clomid is a synthetic drug that prevents action of estrogen on the brain. As a result the brain increases the stimulation of the ovaries which leads to increased estrogen levels and the probability of ovulation. There are two brand names of Clomiphene: Clomid produced by Merrell-Dow, and Serophene manufactured by Serono. Both of these drugs are medical counterparts although Serophene is cheaper. There are also some generic forms of Clomid which cost significantly less.
What Clomid is prescribed for?
Clomid is primarily used to stimulate ovulation. Many women who have no ovulation with the help of Clomid can ovulate.
Is Clomid adviced for women ovulating naturally?
Clomid can be assigned to women ovulating naturally to increase the chances of achieving pregnancy.
Does Clomid reduce fertility?
Antiestrogen effect of Clomid may provoke thickening of cervical mucus. This may hinder sperm to the egg. Treatment may include artificial (vaginal) insemination and, in rare cases, the external control of the level of estrogens.
Clomid can also provoke a thinning of the endometrium which is an unfavorable factor for embryo implantation. If ultrasound identifies a thin endometrium, another treatment that stimulate ovulation can be prescribed.
When should I take Clomid?
You should take 1 tablet of Clomid daily or 50 mg for 5 days. Treatment usually begins with 2-5 day cycle (first day of the cycle is the first day of bleeding. Nowadays Clomid increasingly prescribed from the 2-day cycle.
How to regulate a dose of Clomid?
Women usually start with 50 mg daily for 5 days. If ovulation occurs but the pregnancy from the first cycle does not occur then the Clomid treatment may be repeated in the same dosage for 3-6 cycles. If ovulation during the initial dose does not occur then the dose may be increased to 2 tablets for 5 days of the next cycle.
The use of Clomid in the assigned dosage can be repeated only from 3 to 6 cycles. Maximum dose is 150 mg of Clomiphene, or 3 tablets daily for 5 days. In rare cases you may be designated by 4 tablets or 200 mg per day.
How to determine the ovulation?
There are several different ways of determining the ovulation. Most other methods are used to determine the basal temperature, endometrial biopsy, determination of progesterone or transvaginal ultrasound examination of the follicles. Each of these methods has its pluses and minuses and none of these methods can not reliably determine - whether ovulation has occurred.
What does it mean a "good" analysis of progesterone?
The level of progesterone from 10 to 15 or above shall be considered as satisfactory. If the level of progesterone below you may need to increase a dose of Clomiphene or receive another medications to stimulate ovulation.
Is there any chances to conceive after taking Clomid?
Chances to conceive in the intake of Clomid are 10-13% per cycle of treatment depending on age, cause of infertility, the organism's reaction to this treatment and other drugs that are used in conjunction with Clomid. It is comparable with 20-25% of women with normal fertility. The possibility of conception is increased to 30-60% after 6 cycles of taking Clomiphene.
What are the chances of multiple pregnancy while taking Clomid?
About 5-10% of pregnancies occurring while taking Clomid, ending the birth of twins and less than 1% - the birth of 3 or more children. It compares with 1.2% of twins born to women who did not take Clomid.
Can Clomid cause any abnormalities?
Clomifene is used in the USA since 1967. At the present time there is no evidence that Clomid increases the chance of birth of children with disabilities or how it influences on the growth of children.